JSFiddle - React, Tailwind, and code Playground
HTML
<div class="pdd" id="test">
</div>
CSS
.pdd {
margin-left: var(--m);
margin-top: var(--m);
width: 100px;
height: 100px;
background-color: green;
}
JavaScript
var test = document.getElementById("test");
test.style.setProperty("--m", "20px", "");