JSFiddle - React, Tailwind, and code Playground

HTML

<script src="https://ajax.googleapis.com/ajax/libs/jquery/2.1.1/jquery.min.js"></script>
Press ctrl + s

JavaScript

$(document).ready(function() {
    $(document).keydown(function(event) {
        if (event.ctrlKey && event.keyCode == 83) {
            //action here
            event.preventDefault();
            alert('Saved');
        }
    });
});