JSFiddle - React, Tailwind, and code Playground

HTML

<script src="https://code.jquery.com/jquery-3.5.1.min.js"></script>
<div class="xxx-exclude">
  <button type="button">
  Excluded
  </button>
  <button type="button" class="xxx-include">
  Included
  </button>
</div>
<div>
  <button type="button">
  Included
  </button>
</div>
<button type="button" class="xxx-exclude">
Excluded
</button>

JavaScript

$(".xxx-exclude:not(.xxx-include),.xxx-exclude *:not(.xxx-include)").click(function (e) {
	alert("excluded");
	return false;
});