JSFiddle - React, Tailwind, and code Playground

HTML

<script src="https://rawgit.com/walling/unorm/master/lib/unorm.js"></script>

JavaScript

var teste = "Çaptúra de Tela 2016-04-27 às 18.21.24.png à à";

function removerAcentos(s) {
  return s.normalize('NFD').replace(/[\u0300-\u036f]/g, '');
}

console.log(removerAcentos(teste));