SO jQuery Fiddle
Test Fiddle mainly for SO Questions jQuery 1.4.3, UI 1.8.5
by Nick Craver
HTML
<link rel="stylesheet" href="http://ajax.googleapis.com/ajax/libs/jqueryui/1.8.5/themes/ui-lightness/jquery-ui.css">
<span>Hello world to all people</span>
JavaScript
$("span").html(function(i, t) {
return t.replace(/(world to all)/g, "<i>$1</i>");
});