JSFiddle - React, Tailwind, and code Playground

HTML

<div class="main">
    <div class="one">
        <div class="a box">a</div>
        <div class="b box">b</div>
    </div>
    <div class="two">
        <div class="three">
            <div class="c box">c</div>
            <div class="d box">d</div>
        </div>
        <div class="four box">
            <div class="e">e</div>
        </div>
    </div>

</div>

CSS

.box {
  background-color: green;
  margin: 5px; 
  /* padding: 30px; */
}

.one {
   display: flex; 

}

.a {
  flex: 3;
}

.b {
  flex: 2;
}

.two {
  display: flex;
  
}

.three {
  flex: 2;
}

.four {
  flex: 3;
}