JSFiddle - React, Tailwind, and code Playground

HTML

<div class="A">
    <div class="B">
        <div class="C">234234234</div>
    </div>
    <div class="B">
        <div class="C">234234234</div>
    </div>
    <div class="B">
        <div class="C">sdfsdfsdfsdf</div>
    </div>
</div>

CSS

.A > div > div { 
  background-color:yellow;
}
.A > div:last-child > div:last-child { 
  background-color:red;
}