JSFiddle - React, Tailwind, and code Playground

HTML

<div class="grid fr-only">
  <div>1fr</div>
  <div>2fr</div>
  <div>4fr</div>
  <div>8fr</div>
  <div>16fr</div>
</div>
<div class="grid px-combine">
  <div>1fr</div>
  <div>2fr</div>
  <div>4fr</div>
  <div>160px</div>
  <div>8fr</div>
</div>

CSS

.grid.fr-only {
 display: grid;
 grid-template-columns: 1fr 2fr 4fr 8fr 16fr;
}
.grid.px-combine {
 display: grid;
 grid-template-columns: 1fr 2fr 4fr 160px 8fr;
}
.grid > div {
  background: #8ff;
  border: solid 1px black;
}