JSFiddle - React, Tailwind, and code Playground
JavaScript
var str = "abc,de 55,5gggggg,hhhhhh"
str = str.replace(/([a-zA-Z ])/g, "").replace(/,\s*$/, "");
if (str.match(/,/g).length > 1) // if there's more than one comma
str = str.replace(',', '');
alert (str);