JSFiddle - React, Tailwind, and code Playground

HTML

<textarea id="hui"></textarea>

JavaScript

const handleInput = e => {
    const patternKeywords = /жс.*макака|макака.*жс/;
    const inputText = e.target.value;
    const triggered = patternKeywords.test(inputText);
    if (triggered)
        document.body.style.backgroundColor = "red";
}


document.getElementById("hui").addEventListener("keyup", handleInput);