js replace string (basic) (only replace first match)
HTML
<div class="text_div">
10,000,00
</div>
JavaScript
$(".text_div").text(function () {
return $(this).text().replace(",", "");
});
<div class="text_div">
10,000,00
</div>
$(".text_div").text(function () {
return $(this).text().replace(",", "");
});