Edit in JSFiddle

var myArray = [0, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11];
var diffArray = [3, 4, 5];

// the lodash way 
var cool = _.difference(myArray, diffArray);

// Pure JS
var notCool = [];
for (var i = 0; i < myArray.length; i++) {
    if (diffArray.indexOf(myArray[i]) == -1) {
        notCool.push(myArray[i]);
    }
}
                         
//display it on page
document.getElementById("cool").innerHTML = cool;
document.getElementById("not-cool").innerHTML = notCool;

Lodash result:
<p id="cool"></p>
Pure JS result:
<p id="not-cool"></p>