JSFiddle - React, Tailwind, and code Playground

HTML

<html>
    <body>
        <div id="container">
            <div 
                id="item"
                onclick="playClickAnim(1)"
                onmouseenter="playHooverAnim(1)"
                onmouseout="playHooverAnim(-1)" />
        </div>
    </body>
</html>

CSS

#container {
    background-color: black;
    width: 100%;
    height: 100%;
    position: absolute;
    top:0;
    bottom: 0;
    left: 0;
    right: 0;
    margin: auto;
}

#item {
    position: absolute;
    top: 50%;
    left: 50%;
    transform: translate(-50%, -50%);
    width: 100px;
    height: 100px;
    
    background-color: red;
}

JavaScript

var item = document.getElementById("item");

var introFrames = [
    {"transform": "translate(-50%, -50%) scale(0,0) translate(0, 0)"},
    {"transform": "translate(-50%, -50%) scale(1,1) translate(0, 0)"}
]
var introOpts = {
    "duration": 5000,
    "iterations": 1,
    "easing": "cubic-bezier(0.175, 0.885, 0.32, 1.275)"
}

var introAnim = item.animate(introFrames, introOpts);
introAnim.pause();

var hooverFrames = [
    {"transform": "translate3d(0, 0, 0)"},
    {"transform": "translate3d(-50%, -50%, 0)"}
]
var hooverOpts = {
    "duration": 1000,
    "iterations": 1,
    "easing": "cubic-bezier(0.175, 0.885, 0.32, 1.275)",
    "fill": "both",
    "composite": 'add'
}

var hooverAnim = item.animate(hooverFrames, hooverOpts);
hooverAnim.pause();

var clickFrames = [
    {"transform": "translate(0, 0)"},
    {"transform": "translate(-50%, 0)"},
    {"transform": "translate(0, 0)"}
]
var clickOpts = {
    "duration": 500,
    "iterations": 1,
    "easing": "cubic-bezier(0.175, 0.885, 0.32, 1.275)",
    "fill": "both",
    "composite": 'add'
}

var clickAnim = item.animate(clickFrames, clickOpts);
clickAnim.pause();


introAnim.play();

function playHooverAnim(direction) {
    console.log('HOOVER', direction);
    hooverAnim.playbackRate = direction;
    hooverAnim.play();
}

function playClickAnim() {
    console.log('CLICK');
    clickAnim.play();
}