JSFiddle - React, Tailwind, and code Playground

HTML

<!DOCTYPE html>
<html>
<head>

</head>

<body>

<ul>
    <li>item1</li>
    <li>item2</li>
    <li>item3</li>
    <li>item4</li>
</ul>
   

</body>
</html>

CSS

li:nth-last-child(2)
{
  font:15px arial,sans-serif;
  color:red;
}