JSFiddle - React, Tailwind, and code Playground

HTML

<div id="outerdiv">
    <div id="innerdiv">
        <table>
            <tr>
                <td class="headcol"><div>This is a long label</div></td>
                <td class="hiddenheadcol"><div>This is a long label</div></td>
                <td class="long">QWERTYUIOPASDFGHJKLZXCVBNM</td>
                <td class="long">QWERTYUIOPASDFGHJKLZXCVBNM</td>
            </tr>
            <tr>
                <td class="headcol"><div>Short label</div></td>
                <td class="hiddenheadcol"><div>Short label</div></td>
                <td class="long">QWERTYUIOPASDFGHJKLZXCVBNM</td>
                <td class="long">QWERTYUIOPASDFGHJKLZXCVBNM</td>
            </tr>
        </table>
    </div>
</div>

CSS

body {
    font: 16px Calibri;
}
#outerdiv {
    position: absolute;
    top: 0;
    left: 0;
    right: 0;
    width: 100%;
    border-top: 1px solid grey;
}
#innerdiv {
    overflow-x: scroll;
    margin-left: 100px;
    overflow-y: visible;
    padding-bottom: 1px;
}
table {
    border-collapse:separate;
}
td {
    margin: 0;
    border: 1px solid grey;
    border-top-width: 0;
    border-left-width: 0px;
    padding: 10px;
}
td.headcol {
    position: absolute;
    left: 0;
    top: auto;
    border-bottom-width: 1px;
    padding: 0;
    border-left-width: 1px;
}
td.hiddenheadcol {
    max-width: 0;
    visibility: hidden;
    padding: 0;
}
td.headcol div {
    width: 100px;
    max-width: 100px;
    background: lightblue;
    padding: 10px;
    box-sizing: border-box;
}
td.hiddenheadcol div {
    width: 100px;
    max-width: 100px;
    background: red;
    padding: 10px;
}
td.long {
    background:yellow;
    letter-spacing:1em;
}