Edit in JSFiddle

Result
CSS
HTML

.wrap {
  margin: 2em 3em;
  position: relative;
  border: 1px solid #ccc;
  height: 200px;
  display: inline-block;
  width: 200px;
  white-space: nowrap;
}

.ori,
.trans {
  width: 150px;
  height: 100px;
  border: 1px solid #7a0006;
  background: #cf0009;
  left: 50%;
  top: 50px;
  margin-left: -75px;
  position: absolute;
}

.ori {
  z-index: 0;
  opacity: 0.1;
}

.trans {
  z-index: 10;
  opacity: 0.5;
  background-color: #1564cf;
  transition: transform 1s;
}

.scale:hover {
  transform: scale(2, 3);
}

.scaleX:hover {
  transform: scaleX(0.5);
}

.scaleY:hover {
  transform: scaleY(0.2);
}

<!DOCTYPE html>
<html lang="ko">
  <head></head>
  <body>
    <div class="wrap">
      scaleX(0.5)
      <div class="ori"></div>
      <div class="trans scaleX">scaleX(0.5)</div>
    </div>
    <div class="wrap">
      scaleY(0.2)
      <div class="ori"></div>
      <div class="trans scaleY">scaleY(0.2)</div>
    </div>
    <div class="wrap">
      scale(2,3)
      <div class="ori"></div>
      <div class="trans scale">scale(2,3)</div>
    </div>
  </body>
</html>