JSFiddle - React, Tailwind, and code Playground

HTML

<div>
    <label>Email 1
        <lable/>
        <input class="emailrequerido1" name="email_contactopadrino" id="email_contactopadrino" type="email" value="If there is memorized text the button doesnt enable" />
        <br/>
        <label>Email 2
            <lable/>
            <input class="emailrequerido2" name="email_contactopadrino" id="email_contactopadrino" type="email" />
            <br/>
            <label>Email 3
                <lable/>
                <input class="emailrequerido3" name="email_contactopadrino" id="email_contactopadrino" type="email" />
                <br/>
                <label>Email 4
                    <lable/>
                    <input class="emailrequerido4" name="email_contactopadrino" id="email_contactopadrino" type="email" />
                    <br/>
                    <label>Email 5
                        <lable/>
                        <input class="emailrequerido5" name="email_contactopadrino" id="email_contactopadrino" type="email" />
                        <br/>
                        <button id="enviarForm" type="submit" class="uk-button uk-float-right">Submit</button>
                        <div/>

CSS

.emailrequerido1 {
    width: 300px;
}

JavaScript

$(document).ready(function () {
    var elements = document.getElementsByTagName("INPUT");
    for (var i = 0; i < elements.length; i++) {
        elements[i].oninvalid = function (e) {
            e.target.setCustomValidity("");

            if (!e.target.validity.valid) {
                e.target.setCustomValidity("<?php echo JText::_('COM_CSTUDOMUS_EMAIL_INVALIDO');?>");
            }
        };
        elements[i].oninput = function (e) {
            e.target.setCustomValidity("");
        };
    }

    $("#enviarForm").attr('disabled', true);
    $(":input").bind("keyup change", function (e) {
        var comboVal = $('.emailrequerido1').val() + $('.emailrequerido2').val() + $('.emailrequerido3').val() + $('.emailrequerido4').val() + $('.emailrequerido5').val();
        if (comboVal == 'nullnull' || comboVal == "") {
            $("#enviarForm").attr('disabled', true);
        } else {
            $("#enviarForm").removeAttr('disabled');
        }
    });
});