JSFiddle - React, Tailwind, and code Playground

HTML

<button id="en">Enable/disable</button>
<a id="link" onclick="alert('dude')" href="#">Can you click me?</a>

CSS

#link.disabled{
    z-index:-1;
    position:relative;
    opacity: .5;
}

JavaScript

$("#en").click(function() {
    $("#link").toggleClass("disabled");
});