JSFiddle - React, Tailwind, and code Playground

HTML

<input type="text" id="word"><input type="button" id="replaceButton" value="remove word">

<span id="list">1,2,3</span>

JavaScript

jQuery(document).ready(function($) {
    $("#replaceButton").click(function() {
        // find the word
        var text = $('#word').val();
        
        // create a regex
        var re = new RegExp(text, "gi");
        
        // replace the inner html
        // please note: this may cause serious problems when not used on textnodes
        // see: http://stackoverflow.com/questions/298750/how-do-i-select-text-nodes-with-jquery
        var replacedHTML = $('#list').html().replace(re, "");
        
        // replace
        $('#list').html(replacedHTML);
    });
});