JSFiddle - React, Tailwind, and code Playground

JavaScript

var a = [ "50237451_001", "50237451_100", "50236765_001", "50236765_100" ];
var b = [ "50237451_001", "50237451_100" ];

var minus = function ( a, b ) {
    return a.filter(function ( name ) {
        return b.indexOf( name ) === -1;
    });
};            

var result = minus( a, b );

document.write( result );