JSFiddle - React, Tailwind, and code Playground

HTML

<script src="http://code.jquery.com/jquery-2.0.3.min.js"></script>
<body>
    <script>alert("hello - should happen only once");</script>
    Myword, is hot and its also here Myword.
</body>

JavaScript

t = $('body').clone().find("script").remove().end().html();
t = t.replace(/Myword/g, '<div>Stack Oveflow</div>');
$('body').html(t);