JSFiddle - React, Tailwind, and code Playground

HTML

<table><tbody><tr>
    
    <td class="cartItemTotal">
    <span>
        <span class="currency_sign">£</span>
        25.00
    </span>
</td>
    
    </tr>
    </tbody></table>

JavaScript

var node = $(".cartItemTotal>span").contents().filter(function() {
        return this.nodeType == 3;
    });
node.last().replaceWith( document.createTextNode( "1.99" ));