JSFiddle - React, Tailwind, and code Playground

HTML

<input id='_inputcb_Q801' name='_inputcb_Q801' type='checkbox' checked>
<label id='_inputcb_Q801L' for='_inputcb_Q801'>Text</label>
<button type="button" id="btn">Click Me!</button>

JavaScript

$("#btn")
    .click( 
        function(){
           $('input[name=_inputcb_Q801]').prop('checked',false);
        });