JSFiddle - React, Tailwind, and code Playground

HTML

<h1>Page Title</h1>

<div id="content">
    <div class="group">
        <div class="item">Item</div>
        <div class="item">Item</div>
        <div class="item">Item</div>
        <div class="item">Item</div>
        <div class="item">Item</div>
        <div class="item">Item</div>
        <div class="item">Item</div>
        <div class="item">Item</div>
        <div class="item">Item</div>
        <div class="item">Item</div>
        <div class="item">Item</div>
        <div class="item">Item</div>
        <div class="item">Item</div>
        <div class="item">Item</div>
        <div class="item">Item</div>
    </div>
    
    <div class="group">
        <div class="item">Item</div>
        <div class="item">Item</div>
        <div class="item">Item</div>
        <div class="item">Item</div>
        <div class="item">Item</div>
    </div>
    
    <div class="group">
        <div class="item">Item</div>
        <div class="item">Item</div>
        <div class="item">Item</div>
        <div class="item">Item</div>
        <div class="item">Item</div>
    </div>
</div>

CSS

html {
    height: 100%;
}

body {
    height: 100%;
    display: flex;
    flex-flow: column nowrap;
}

h1 {
    padding: 1em;
}

#content {
    padding: 10px;
    background-color: #eee;
    display: flex;
    flex-grow: 1;
}

#content > .group {
    margin: 10px;
    padding: 10px;
    border: 1px solid #cfcfcf;
    background-color: #ddd;
    flex: 1 1 auto;
}

#content > .group:first-child {
    columns: 10em;
    flex-grow: 2;    
}

#content > .group .item {
    margin: 10px;
    padding: 10px;
    background-color: #aaa;
    break-inside: avoid;
}

#content > .group .item:first-child {
    margin-top: 0;
}