JSFiddle - React, Tailwind, and code Playground
HTML
<body>
<!-- Not really a video, but it will be... -->
<div id="video">
<video poster="http://placekitten.com/1000/1000"></video>
</div>
<div id="wrapper">
<div id="cutter">
<p>Hello, I want this div to cut through to the "video," through the solid body... like a clear window.</p>
<p>I made the #wrapper a little transparent so you could see there is something under it, but the idea is that it would be opaque.</p>
</div>
</div>
</body>
CSS
#video { position: fixed; height: 100%; width: 100%; z-index: -5; }
/* Made a bit transparent so you can see what we're cutting through to */
#wrapper { position: fixed; height: 100%; width: 100%; z-index: 5; background: rgba(200, 54, 54, 0.9); }
#cutter {
background: lightgray;
height: 400px;
width: 400px;
margin: 50px;
padding: 1px 15px;
}