JSFiddle - React, Tailwind, and code Playground

HTML

<div>Press ctrl + x + enter in this window</div>

JavaScript

var    keys = [];

window.executeHotkeyTest = function(callback,keyValues){
    if(typeof callback !== "function")
        throw new TypeError("Expected callback as first argument");
    if(typeof keyValues !== "object" && (!Array.isArray || Array.isArray(keyValues)))
        throw new TypeError("Expected array as second argument");
    
    var allKeysValid = true;
    
    for(var i = 0; i < keyValues.length; ++i)
        allKeysValid = allKeysValid && keys[keyValues[i]];

    if(allKeysValid)
        callback();
};

window.addGlobalHotkey = function(callback,keyValues){
    if(typeof keyValues === "number")
        keyValues = [keyValues];
    
    var fnc = function(cb,val){
        return function(e){
            keys[e.keyCode] = true;
            executeHotkeyTest(cb,val);
        };        
    }(callback,keyValues);
    window.addEventListener('keydown',fnc);
    return fnc;
};

window.addEventListener('keyup',function(e){
    keys[e.keyCode] = false;
});

addGlobalHotkey(function(){
    document.body.appendChild(
        document.createElement('div').appendChild(
            document.createTextNode('Ctrl + x + Enter down')
    ).parentNode);
},[88,13,17]);