JSFiddle - React, Tailwind, and code Playground

HTML

<table>
    <tr>
        <td class="cartItemTotal"> 
            <span>
                <span class="currency_sign">£</span>
                25.00
            </span>
        </td>
    </tr>
</table>

JavaScript

$('.currency_sign').get(0).nextSibling.nodeValue = '43.00';