JSFiddle - React, Tailwind, and code Playground

HTML

<span style="font-style: italic;">cultura</span>l <span style="font-weight: bold;">heart</span>
<span style="font-family: Courier" lang="EN-US">May</span>

JavaScript

$('*').each(function() {
    var s = this.style;
    for (var i = s.length - 1; i >= 0; i--)
       if (s[i] != 'font-weight')
           s.removeProperty(s[i]);
});