JSFiddle - React, Tailwind, and code Playground

HTML

<div class="container">
    <div class="bg-image"></div>
    <div class="highlight-region" style="top:50px;left:50px;background-position: -50px -50px;"></div>
    <div class="highlight-region" style="top:150px;left:150px;background-position: -150px -150px;"></div>
</div>

CSS

.container {
    position:relative;
    height:455px;
    width:606px;
}

.container div {
    position:absolute;
    background-image:url(http://www.beachphotos.cn/wp-content/uploads/2010/07/indoensianbeach.jpg);
}

.container .bg-image {
    opacity:0.3;
    height:455px;
    width:606px;
}

.container div.highlight-region {
    height:50px; 
    width:50px;
    opacity:0;
}

.container div.highlight-region:hover {
    opacity:1;
}