JSFiddle - React, Tailwind, and code Playground

HTML

<div class="item">
    <div class="item">
        select me
        <div class="item">don't select me</div>
    </div>
    <span>
        <div class="item">select me</div>
    </span>
</div>

JavaScript

var firstItem = $('.item:first');
var selector = firstItem.find('.item');
selector.css('color', 'red');