JSFiddle - React, Tailwind, and code Playground

HTML

<ul class="first">
  <li>
    <div class="tg-hey">hey</div>
    <div class="tg-hi">hi</div>
    <div class="tg-hoi">hoi</div>
  </li>
</ul>
<ul class="second">
  <li>
    <div class="tg-hey">hey</div>
    <div class="tg-hi">hi</div>
    <div class="tg-hoi">hoi</div>
  </li>
</ul>
<ul class="third">
  <li>
    <div class="tg-hey">hey</div>
    <div class="tg-hi">hi</div>
    <div class="tg-hoi">hoi</div>
  </li>
</ul>

JavaScript

if($(".second:has(.tg-hey)").length) {
    alert("hello");
}